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Cyclobenzaprine has major contraindications with monoamine oxidase inhibitors (MAOIs). At least one study also found increased risk of serotonin syndrome when cyclobenzaprine was taken with the serotonergic drugs duloxetine or phenelzine. [26] These substances may interact with cyclobenzaprine:
The statement that cyclobenzaprine should not be taken with SSRIs is not entirely correct. The cited source (Keegan et al, 2006) indicates hyperserotonemia with an M.A.O.I . This fits the contraindication profile of M.A.O.I. drugs in general. Keegan et al also found some risk between cyclobenzaprine and a relatively new SSNRI, duloxetine.
SNRIs are another class of modern antidepressants. Common SNRIs include Cymbalta (duloxetine), Effexor XR (venlafaxine) and Pristiq (desvenlafaxine). Tricyclic antidepressants (TCAs). Tricyclic ...
Duloxetine, sold under the brand name Cymbalta among others, [1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. [10] [11] It is taken by mouth. [10] Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI ...
SNRIs. The most commonly prescribed SNRIs are: Venlafaxine (Effexor XR) Desvenlafaxine (Pristiq) Duloxetine (Cymbalta). Milnacipran (Savella) Levomilnacipran (Fetzima)
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
In contrast, escitalopram, duloxetine, paroxetine, venlafaxine (Effexor), and citalopram were associated with more weight gain. Fluoxetine (Prozac) was similar to sertraline when it came to this ...
Less often, SRIs are also used to treat a variety of other medical conditions including neuropathic pain and fibromyalgia (e.g., duloxetine, milnacipran), and premature ejaculation (e.g., dapoxetine) as well as for dieting (e.g., sibutramine).