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The cerebral aqueduct (aqueduct of the midbrain, aqueduct of Sylvius, Sylvian aqueduct, mesencephalic duct) is a small, narrow tube connecting the third and fourth ventricles of the brain. [ 1 ] [ 2 ] The cerebral aqueduct is a midline structure that passes through the midbrain .
The aqueduct of Sylvius is the channel which connects the third ventricle to the fourth ventricle and is the narrowest part of the CSF pathway with a mean cross-sectional area of 0.5 mm 2 in children and 0.8 mm 2 in adults. [3] Because of its small size, the aqueduct is the most likely place for a blockage of CSF in the ventricular system.
The cerebral aqueduct is a narrow channel located between the tectum and the tegmentum, and is surrounded by the periaqueductal grey, [9] which has a role in analgesia, quiescence, and bonding. The dorsal raphe nucleus (which releases serotonin in response to certain neural activity) is located at the ventral side of the periaqueductal grey, at ...
Cerebral peduncle. Crus cerebri; Mesencephalic cranial nerve nuclei. Oculomotor nucleus (III) Edinger-Westphal nucleus; Trochlear nucleus (IV) Mesencephalic duct (cerebral aqueduct, aqueduct of Sylvius)
The narrowness of the cerebral aqueduct and foramina means that they can become blocked, for example, by blood following a hemorrhagic stroke. As cerebrospinal fluid is continually produced by the choroid plexus within the ventricles, a blockage of outflow leads to increasingly high pressure in the lateral ventricles.
The third ventricle is a narrow, laterally flattened, vaguely rectangular region, filled with cerebrospinal fluid, and lined by ependyma.It is connected at the superior anterior corner to the lateral ventricles, by the interventricular foramina, and becomes the cerebral aqueduct (aqueduct of Sylvius) at the posterior caudal corner.
A single duct, the cerebral aqueduct between the pons and the cerebellum, connects the third ventricle to the fourth ventricle. [50] Three separate openings, the middle and two lateral apertures, drain the cerebrospinal fluid from the fourth ventricle to the cisterna magna, one of the major cisterns.
The fourth ventricle extends from the cerebral aqueduct (aqueduct of Sylvius) to the obex, and is filled with cerebrospinal fluid (CSF). The fourth ventricle has a characteristic diamond shape in cross-sections of the human brain. It is located within the pons or in the upper part of the medulla oblongata.