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  2. Quasi-experiment - Wikipedia

    en.wikipedia.org/wiki/Quasi-experiment

    A quasi-experiment is an empirical interventional study used to estimate the causal impact of an intervention on target population without random assignment.Quasi-experimental research shares similarities with the traditional experimental design or randomized controlled trial, but it specifically lacks the element of random assignment to treatment or control.

  3. Clinical study design - Wikipedia

    en.wikipedia.org/wiki/Clinical_study_design

    Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...

  4. Design of experiments - Wikipedia

    en.wikipedia.org/wiki/Design_of_experiments

    An experimental design or randomized clinical trial requires careful consideration of several factors before actually doing the experiment. [32] An experimental design is the laying out of a detailed experimental plan in advance of doing the experiment.

  5. Regression discontinuity design - Wikipedia

    en.wikipedia.org/.../Regression_discontinuity_design

    The RD design takes the shape of a quasi-experimental research design with a clear structure that is devoid of randomized experimental features. Several aspects deny the RD designs an allowance for a status quo. For instance, the designs often involve serious issues that do not offer room for random experiments.

  6. Adaptive design (medicine) - Wikipedia

    en.wikipedia.org/wiki/Adaptive_design_(medicine)

    This is in contrast to traditional single-arm (i.e. non-randomized) clinical trials or randomized clinical trials (RCTs) that are static in their protocol and do not modify any parameters until the trial is completed. The adaptation process takes place at certain points in the trial, prescribed in the trial protocol.

  7. Natural experiment - Wikipedia

    en.wikipedia.org/wiki/Natural_experiment

    This study was an example of a natural experiment, called a case-crossover experiment, where the exposure is removed for a time and then returned. The study also noted its own weaknesses which potentially suggest that the inability to control variables in natural experiments can impede investigators from drawing firm conclusions.' [ 12 ]

  8. Pragmatic clinical trial - Wikipedia

    en.wikipedia.org/wiki/Pragmatic_clinical_trial

    The distinction between pragmatic and explanatory trials is not the same as the distinction between randomized and nonrandomized trials. Any trial can be either randomized or nonrandomized and have any degree of pragmatic and explanatory power, depending on its study design, with randomization being preferable if practicably available.

  9. Multiple baseline design - Wikipedia

    en.wikipedia.org/wiki/Multiple_Baseline_Design

    Ex post facto recruitment methods are not considered true experiments, due to the limits of experimental control or randomized control that the experimenter has over the trait. This is because a control group may necessarily be selected from a discrete separate population. This research design is thus considered a quasi-experimental design.