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Loratadine is a tricyclic antihistamine, which acts as a selective inverse agonist of peripheral histamine H 1 receptors. [ 22 ] [ 26 ] The potency of second generation histamine antagonists is (from strongest to weakest) desloratadine ( K i 0.4 nM) > levocetirizine (K i 3 nM) > cetirizine (K i 6 nM) > fexofenadine (K i 10 nM) > terfenadine ...
An H 3-antihistamine is a classification of drugs used to inhibit the action of histamine at the H 3 receptor. H 3 receptors are primarily found in the brain and are ...
Bilastine is an antihistamine medication used to treat hives (), allergic rhinitis and itchy inflamed eyes (allergic conjunctivitis) caused by an allergy. [6] It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H 1 receptor, preventing these allergic reactions. [7]
Tripelennamine, sold under the brand name Pyribenzamine by Novartis, is a drug that is used as an antipruritic and first-generation antihistamine. It can be used in the treatment of asthma, hay fever, rhinitis, and urticaria, but is now less common as it has been replaced by newer antihistamines. The drug was patented at CIBA, which merged with ...
Cetirizine is a second-generation antihistamine used to treat allergic rhinitis (hay fever), dermatitis, and urticaria (hives). [11] It is taken by mouth. [12] Effects generally begin within thirty minutes and last for about a day. [12]
A Clarinase Repetab tablet contains 5 mg loratadine in the tablet coating and 120 mg pseudoephedrine sulfate equally distributed between the tablet coating and the barrier-coated core. The two active components in the coating are quickly liberated; release of pseudoephedrine in the core is delayed for several hours.
Cyclizine is a piperazine derivative with histamine H 1-receptor antagonist (antihistamine) activity. The precise mechanism of action in inhibiting the symptoms of motion sickness is not well understood. It may have effects directly on the vestibular system and on the chemoreceptor trigger zone.
Carbinoxamine is an antihistamine and anticholinergic agent. It is used for hay fever, vasomotor rhinitis, mild urticaria, angioedema, dermatographism and allergic conjunctivitis. Carbinoxamine is a histamine antagonist, specifically an H1-antagonist. The maleic acid salt of the levorotatory isomer is sold as the prescription drug rotoxamine.
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