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Current Medicinal Chemistry is a peer-reviewed medical journal published by Bentham Science Publishers. The editor-in-chief is Atta-ur-Rahman, FRS (Kings College University of Cambridge Cambridge, UK). The journal covers developments in medicinal chemistry and rational drug design and publishes original research reports and review papers. [2]
Current Topics in Medicinal Chemistry is a biweekly peer-reviewed medical journal published by Bentham Science Publishers. It includes review articles on all aspects of medicinal chemistry, including drug design. The current editor-in-chief is Jia Zhou (University of Texas, Medical Branch).
Description: An encyclopedic text and reference suitable for advanced undergraduate or graduate study. Importance: This massive text by outstanding research workers begins with simple systems and proceeds logically to the more complex phenomena of physical chemistry. The original literature is cited extensively, making the work useful as a ...
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use.
Modified GRM molecules [45] [46] have also been developed that enable the attachment of the linker with the term ADCidified describing the medicinal chemistry process of payload optimization to facilitate linker attachment. [47] Alternatives to small molecule payloads have also been investigated, for example, siRNA. [48]
In the fields of medicine, biotechnology, and pharmacology, drug discovery is the process by which new candidate medications are discovered. [1]Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by serendipitous discovery, as with penicillin.
Kaempferol (3,4′,5,7-tetrahydroxyflavone) is a natural flavonol, a type of flavonoid, found in a variety of plants and plant-derived foods including kale, beans, tea, spinach, and broccoli. [1] Kaempferol is a yellow crystalline solid with a melting point of 276–278 °C (529–532 °F).
The structure of ajoene was determined and it was synthesized based on biosynthetic considerations in 1984, [1] correcting an incorrect structure published in 1983. [2] A short, scalable total synthesis of ajoene was reported in 2018 by Wirth and coworkers [3] while a biosynthetically modeled synthesis of trifluoroajoene from difluoroallicin was published in 2017. [4]