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Prolonged fatigue is fatigue that persists for more than a month, and chronic fatigue is fatigue that lasts at least six consecutive months, which may be caused by a physical or psychological illness, or may be idiopathic (no known cause). [1] Chronic fatigue with a known cause is twice as common as idiopathic chronic fatigue. [6]
The Canadian Consensus Criteria require "post exertional malaise and/or [post exertional] fatigue" instead. [20] [21] [22] [18] [23] On the other hand, the older Oxford Criteria lack any mention of PEM, [24] and the Fukuda Criteria consider it optional. Depending on the definition of ME/CFS used, PEM is present in 60 to 100% of ME/CFS patients. [6]
Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Diagnosis is often based on symptoms and confirmed by genetic testing or skin biopsy, particularly with hEDS, but people may initially be misdiagnosed with hypochondriasis, depression, or myalgic encephalomyelitis/chronic fatigue syndrome. [4] Genetic testing can be used to confirm all other types of EDS. [9]
fatigue – this is common in autoimmune diseases, and is the patient's primary concern [9] malaise; fever [10] These can be the initial presentation for some patients. [3] Other symptoms associated with UCTD include : [11] joint pain – the most common symptom, occurring in up to 86% of patients. [3]
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Lethargy is a state of tiredness, sleepiness, weariness, fatigue, sluggishness, or lack of energy. It can be accompanied by depression , decreased motivation, or apathy . Lethargy can be a normal response to inadequate sleep, overexertion, overworking, stress, lack of exercise, improper nutrition, drug abuse, boredom , or a symptom of an ...