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Early trials in women with PCOS found that metformin helped give a small benefit in insulin sensitivity, reduced weight and helped restore periods, Dr. Ohri says. Because of this, metformin is ...
That said, a 2013 study on people without diabetes who were overweight or had obesity found that those taking metformin lost between 5.6 and 6.5 percent of their body weight. In contrast, the ...
Osteoporosis in the vertebrae can cause serious problems for women. A fracture in this area can happen during day-to-day activities like climbing stairs, lifting objects, or bending forward when ...
Preliminary studies have examined whether metformin can reduce the risk of Alzheimer's disease and whether there is a correlation between type 2 diabetes and the risk of Alzheimer's disease. [247] [248] While metformin may reduce body weight in persons with fragile X syndrome, whether it improves neurological or psychiatric symptoms is uncertain.
Unlike osteoporosis, osteopenia does not usually cause symptoms, and losing bone density in itself does not cause pain. There is no single cause for osteopenia, although there are several risk factors, including modifiable (behavioral, including dietary and use of certain drugs) and non-modifiable (for instance, loss of bone mass with age).
The Women's Health Initiative (WHI) is an ongoing study of over 27,000 women that began in 1991, with the most recent analyses suggesting that, when initiated within 10 years of menopause, HRT reduces all-cause mortality and risks of coronary disease, osteoporosis, and dementia; after 10 years the beneficial effects on mortality and coronary ...
Metformin can also cause a vitamin B12 deficiency, which may be linked with anemia. Stopping the medication or starting vitamin B12 supplementation appears to reverse this. Seek medical advice if ...
[21] [26] Decreased estrogen is a common cause of osteoporosis that can be seen in other conditions such as ovariectomy, ovarian failure, anorexia, and hyperprolactinaemia. [ 41 ] Osteoblastic synthesis of bone does not increase to compensate for the accelerated bone resorption as the lower estrogen levels result in increased rates of ...
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