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A meta-analysis for associations between PFASs and human clinical biomarkers for liver injury, analyzing PFAS effects on liver biomarkers and histological data from rodent experimental studies, concluded that evidence exists that PFOA, perfluorohexanesulfonic acid (PFHxS), and perfluorononanoic acid (PFNA) caused hepatotoxicity in humans. [81]
English: Effects of exposure to PFASs (per- and polyfluoroalkyl substances) on human health Español : Efectos de las PFAS ( sustancias perfluoroalquiladas y polifluoroalquiladas ) en la salud humana
Story at a glance A group of potentially harmful chemicals called per- and polyfluoroalkyl substances (PFAS) have repeatedly cropped up in headlines. But the sheer number of chemicals in this ...
10 January 2018 According to the U.S. Department of Health & Human Services's Agency for Toxic Substances and Disease Registry (ATSDR) website, which was last reviewed on10 January 2018, the "health effects of PFOS, PFOA, PFHxS, and PFNA have been more widely studied than other per- and polyfluoroalkyl substances (PFAS). Some, but not all ...
Fire-retardant foam, which contained PFAS compounds for decades, often found use at military bases and airstrips, causing costly pollution to nearby water sources. The U.S. Department of Defense ...
In humans, PFHxS binds to blood albumin, [8] and relatively little PFHxS is found in the liver compared to longer chain PFASs such as PFOS. [9] The half-life of PFHxS in adult blood serum is 5.3 years (4.7 years for women and 7.4 years for men). [10] The half-life of PFASs in human blood generally decreases with decreasing backbone (CF 2) length.
PFAS has been found in almost all human blood samples tested, one study found 97% of Americans has PFAS in their blood. [29] PFAS chemicals have been linked to high cholesterol, [ 30 ] altered kidney and thyroid function, [ 31 ] ulcerative colitis, [ 32 ] immunosuppression, [ 33 ] decreased effectiveness of vaccines, [ 34 ] low birth weight ...
PFAS contamination negatively impacted adjoining communities, including Art Schapp, a fifth-generation dairy farmer in Clovis who was forced to euthanize his herd of 3,665 cows because of PFAS ...