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Collagenous colitis is an inflammatory condition of the colon.Together with the related condition lymphocytic colitis, it is a subtype of microscopic colitis, which is characterized by inflammation that specifically affects the colon (i.e. colitis), and a clinical presentation that involves watery diarrhea but a lack of rectal bleeding.
Microscopic colitis refers to two related medical conditions which cause diarrhea: collagenous colitis and lymphocytic colitis. [ 2 ] [ 3 ] Both conditions are characterized by the presence of chronic non-bloody watery diarrhea , normal appearances on colonoscopy and characteristic histopathology findings of inflammatory cells.
The signs and symptoms of colitis are quite variable and dependent on the cause of the given colitis and factors that modify its course and severity. [2]Common symptoms of colitis may include: mild to severe abdominal pains and tenderness (depending on the stage of the disease), persistent hemorrhagic diarrhea with pus either present or absent in the stools, fecal incontinence, flatulence ...
Some 17,000 people in the UK are diagnosed with microscopic colitis - a debilitating condition which leads to inflammation of the large bowel and can cause symptoms including stomach pain, fatigue ...
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Compare that to stool transplants for Cassaday’s condition, ulcerative colitis, which Grinspan says leads to an improvement in about 25% of people, with 10% improving after taking a placebo.
However, Ulcerative Colitis can in most cases be cured by proctocolectomy, although this may not eliminate extra-intestinal symptoms. An ileostomy will collect feces in a bag. Alternatively, a pouch can be created from the small intestine; this serves as the rectum and prevents the need for a permanent ileostomy.
However, ulcerative colitis usually affects the rectum and inflammation in IBD extends to areas of the colon without diverticulosis. [1] Additional causes of colitis should be evaluated, including infectious and medication-induced, particularly NSAID-associated. [1] Laboratory results are usually normal in individuals with SCAD.