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Psoriatic erythroderma can be congenital or secondary to an environmental trigger. [12] [13] [14] Environmental triggers that have been documented include sunburn, skin trauma, psychological stress, systemic illness, alcoholism, drug exposure, chemical exposure (e.g., topical tar, computed tomography contrast material), and the sudden cessation of medication.
Pictures of a person with psoriasis (and psoriatic arthritis) at baseline and eight weeks after initiation of infliximab therapy. Psoriasis resistant to topical treatment and phototherapy may be treated with systemic therapies including medications by mouth or injectable treatments. [97]
Erythroderma is generalized exfoliative dermatitis, which involves 90% or more of the patient's skin. [3] The most common cause of erythroderma is exacerbation of an underlying skin disease, such as Harlequin-type ichthyosis, psoriasis, contact dermatitis, seborrheic dermatitis, lichen planus, pityriasis rubra pilaris or a drug reaction, such as the use of topical steroids. [4]
Withdrawal or administration of certain drugs in the patient's previous medication regimen may be required. Oral retinoids are the most effective treatment, and are considered first line. [2] Cyclosporine or infliximab may be required for particularly acute cases. [5] [6]
Psoriatic arthritis; Psoriatic erythroderma; Pustular psoriasis; Pustular psoriasis of the Barber type; Pustular psoriasis of the extremities; Pustular psoriasis of von Zumbusch; Pustulosis palmaris et plantaris
Happily, there’s a host of treatment options to choose from that can effectively address those issues, smoothing, firming, and lifting skin to defy what God—and your habits—gave you.
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