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Vitamin and mineral management for dialysis patients is a required treatment for people undergoing dialysis because during end-stage kidney disease and dialysis the kidneys are functioning at less than 15% of normal levels. [1] As a consequence, certain vitamin and mineral restrictions and supplementations are needed. [2]
Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting conflicting results. No effect of vitamin C supplementation reported for overall mortality. [104]
Vitamin C administration may also acidify the urine and could promote the precipitation of kidney stones or drugs in the urine. [20] Although vitamin C can be well tolerated at doses well above what government organizations recommend, adverse effects can occur at doses above 3 grams per day.
Low activated vitamin D 3 levels are a result of the damaged kidneys' inability to convert vitamin D 3 into its active form, calcitriol, and result in further hypocalcemia. High levels of fibroblast growth factor 23 seem now to be the most important cause of decreased calcitriol levels in CKD patients. [citation needed]
The conversion of 25(OH) vitamin D to 1,25(OH)2 vitamin D is impaired, reducing intestinal calcium absorption and increasing PTH. [2] The kidney fails to respond adequately to PTH, which normally promotes phosphaturia and calcium reabsorption, or to FGF-23, which also enhances phosphate excretion. [2]
The U.S. Preventive Services Task Force say vitamin D supplements do not reduce the risk of falls or bone fractures in healthy older adults. The draft recommendation notes vitamin D can be helpful ...
Side effects from vitamin overdoses may occur, especially in patients with kidney failure. In very large doses, vitamin C in kidney-failure patients can cause severe side effects such as oxalate deposits in bone and soft tissues and may interfere with the absorption and metabolism of vitamin B 12. The product contains 1 g of vitamin C per ...
Diabetes: "Gum disease and diabetes have a bidirectional relationship, meaning that gum disease can make it harder to control blood sugar levels, and uncontrolled diabetes can increase the risk of ...
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