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Treatment of hepatocellular carcinoma varies by the stage of disease, a person's likelihood to tolerate surgery, and availability of liver transplantation: Curative intention: for limited disease, when the cancer is limited to one or more areas of within the liver, surgically removing the malignant cells may be curative.
For example, it is recommended that people with chronic liver disease who are at risk for hepatocellular carcinoma be screened every 6 months using ultrasound imaging. [ 8 ] Because liver cancer is an umbrella term for many types of cancer, the signs and symptoms depend on what type of cancer is present.
Transformation to hepatocellular carcinoma is more common in men. [2] Currently, if the hepatic adenoma is >5 cm, increasing in size, symptomatic lesions, has molecular markers associated with HCC transformation, rising level of liver tumor markers such as alpha fetoprotein , the patient is a male, or has a glycogen storage disorder , the ...
Chronic hepatitis C is a major cause of liver cirrhosis and hepatocellular carcinoma. [132] It is a common medical reason for liver transplantation due to its severe complications. [ 132 ] It is estimated that 130–180 million people in the world are affected by this disease representing a little more than 3% of the world population.
People get liver cancer (also called hepatocellular carcinoma, HCC or hepatoma) typically from a prolonged Hepatitis B or C infection or as a result of cirrhosis from chronic alcoholism. Liver cancer may bring about yellowing of the skin and eyes ( jaundice ), itching ( pruritus ), or cause a buildup of fluid in the abdomen ( ascites ).
Hepatocellular carcinoma; Causes. The list of conditions associated with chronic liver disease is extensive and can be categorised in the following way: [3]
Primary liver cancer most commonly manifests as hepatocellular carcinoma or cholangiocarcinoma; rarer forms include angiosarcoma and hemangiosarcoma of the liver. (Many liver malignancies are secondary lesions that have metastasized from primary cancers in the gastrointestinal tract and other organs, such as the kidneys, lungs.) [16]
Viral hepatitis is liver inflammation due to a viral infection. [1] [2] It may present in acute form as a recent infection with relatively rapid onset, or in chronic form, typically progressing from a long-lasting asymptomatic condition up to a decompensated hepatic disease and hepatocellular carcinoma (HCC).