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Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...
The DSM-5 allows for diagnosis of the predominantly inattentive presentations of ADHD (ICD-10 code F90.0) if the individual presents six or more (five for adults) of the following symptoms of inattention for at least six months to a point that is disruptive and inappropriate for developmental level:
[3] [6] The International Classification of Diseases 11th Revision also updated its diagnostic criteria to better align with the new DSM-5 criteria, but in a change from the DSM-5 and the ICD-10, while it lists the key characteristics of ADHD, the ICD-11 does not specify an age of onset, the required number of symptoms that should be exhibited ...
The DSM-IV criteria for diagnosis of ADHD is 3–4 times more likely to diagnose ADHD than is the ICD-10 criteria. [212] ADHD is alternately classified as neurodevelopmental disorder [213] or a disruptive behaviour disorder along with ODD, CD, and antisocial personality disorder. [214] A diagnosis does not imply a neurological disorder. [185]
DIHS is a delayed onset drug eruption, often occurring a few weeks to 3 months after initiation of a drug. [2] Worsening of systemic symptoms occurs 3–4 days after cessation of the offending drug. [5] There are genetic risk alleles that are predictive of the development of DIHS for particular drugs and ethnic populations. [5]
When these symptoms occur the allergic reaction is called anaphylaxis. [9] Anaphylaxis occurs when IgE antibodies are involved, [10] and areas of the body that are not in direct contact with the food become affected and show severe symptoms. [9] [11] Untreated, this can proceed to vasodilation, a low blood pressure situation called anaphylactic ...
Anaphylactoid reaction, non-immune anaphylaxis, or pseudoanaphylaxis, is a type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation. [ 10 ] [ 42 ] Non-immune anaphylaxis is the current term, as of 2018, used by the World Allergy Organization [ 42 ] with some recommending that the old ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...