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The supplement's two main ingredients, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) help promote healthy blood flow and regulate serotonin, AKA the “feel good” hormone.
The supplement provides an all-natural approach to brain health and contains key ingredients such as 5-HTP, which is a precursor to serotonin, a neurotransmitter that plays significant roles in ...
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Melatonin, also known as N-acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N-acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.
Etryptamine [α-Ethyltryptamine (αET)] (Monase) – non-selective serotonin receptor agonist, SNDRA, and weak RIMA; Indeloxazine (Elen, Noin) – serotonin releasing agent (SRA), NRI, and NMDA receptor antagonist; Oxaflozane (Conflictan) – 5-HT 1A, 5-HT 2A, and 5-HT 2C receptor agonist; Pivagabine (Tonerg) – unknown/unclear mechanism of action
Serotonin is an endogenous non-selective agonist for the 5-HT 2C receptor with a binding constant of K i = 16.0 nM. When serotonin binds to the receptors, the most important contacts are in TM helixes 3, 5 and 6 (Figure 3), while the other four TM helixes do not interact directly with the serotonin compound.
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