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The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.
This probability is given by the integral of this variable's PDF over that range—that is, it is given by the area under the density function but above the horizontal axis and between the lowest and greatest values of the range. The probability density function is nonnegative everywhere, and the area under the entire curve is equal to 1.
This method was further developed and employed by Archimedes in the 3rd century BC and used to calculate the area of a circle, the surface area and volume of a sphere, area of an ellipse, the area under a parabola, the volume of a segment of a paraboloid of revolution, the volume of a segment of a hyperboloid of revolution, and the area of a ...
One can often quickly calculate this using the PV diagram as it is simply the area enclosed by the cycle. [citation needed] Note that in some cases specific volume will be plotted on the x-axis instead of volume, in which case the area under the curve represents work per unit mass of the working fluid (i.e. J/kg). [citation needed]
The area of the surface of a sphere is equal to quadruple the area of a great circle of this sphere. The area of a segment of the parabola cut from it by a straight line is 4/3 the area of the triangle inscribed in this segment. For the proof of the results Archimedes used the Method of exhaustion of Eudoxus.
The area of a small horizontal "slab" under the graph of f, of height dy, is equal to the measure of the slab's width times dy: ({() >}). The Lebesgue integral may then be defined by adding up the areas of these horizontal slabs. From this perspective, a key difference with the Riemann integral is that the "slabs" are no longer rectangular ...
Taking an example, the area under the curve y = x 2 over [0, 2] can be procedurally computed using Riemann's method. The interval [0, 2] is firstly divided into n subintervals, each of which is given a width of 2 n {\displaystyle {\tfrac {2}{n}}} ; these are the widths of the Riemann rectangles (hereafter "boxes").
The trajectory of a particle (in red) along a curve inside a vector field. Starting from a, the particle traces the path C along the vector field F. The dot product (green line) of its tangent vector (red arrow) and the field vector (blue arrow) defines an area under a curve, which is equivalent to the path's line integral.
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