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The synergy between trimethoprim and sulfamethoxazole was first described in the late 1960s. [25] [26] [27] Trimethoprim and sulfamethoxazole have a greater effect when given together than when given separately, because they inhibit successive steps in the folate synthesis pathway. They are given in a one-to-five ratio in their tablet ...
Drug reaction with eosinophilia and systemic symptoms; Toxic epidermal necrolysis [c] Ataxia [d] Clostridioides difficile colitis; Aseptic meningitis [e] Pseudomembranous colitis; Interstitial nephritis; Fulminant hepatic necrosis; Hypersensitivity of the respiratory tract; Sore throat; Pallor; Arthralgia
Link between risk of IE & dental procedures or other invasive procedures; Identify & have awareness of early signs/symptoms of infective endocarditis; Know when to seek help/treatment when IE suspected; Review any patients with significant risk of IE if they develop a dental infection, and manage without delay to minimize risk of IE development.
Sulfamethoxazole (SMZ or SMX) is an antibiotic. It is used for bacterial infections such as urinary tract infections , bronchitis , and prostatitis and is effective against both gram negative and positive bacteria such as Escherichia coli and Listeria monocytogenes .
A dental abscess is a localized collection of pus associated with a tooth. The most common type of dental abscess is a periapical abscess, and the second most common is a periodontal abscess. In a periapical abscess, usually the origin is a bacterial infection that has accumulated in the soft, often dead, pulp of the tooth.
Sulfamethoxazole: Gantanol Sulfanilimide (archaic) Sulfasalazine: Azulfidine Sulfisoxazole: Gantrisin Trimethoprim-Sulfamethoxazole (Co-trimoxazole) Bactrim, Septra Sulfonamidochrysoidine (archaic) Prontosil: Tetracyclines(Bs) Demeclocycline: Declomycin