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The synergy between trimethoprim and sulfamethoxazole was first described in the late 1960s. [25] [26] [27] Trimethoprim and sulfamethoxazole have a greater effect when given together than when given separately, because they inhibit successive steps in the folate synthesis pathway. They are given in a one-to-five ratio in their tablet ...
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS.
Sulfamethoxazole (SMZ or SMX) is an antibiotic. It is used for bacterial infections such as urinary tract infections , bronchitis , and prostatitis and is effective against both gram negative and positive bacteria such as Escherichia coli and Listeria monocytogenes .
The following is a list of antibiotics. ... Trimethoprim-Sulfamethoxazole (Co-trimoxazole) Bactrim, Septra Sulfonamidochrysoidine (archaic) Prontosil:
Certain sulfonamides (sulfadiazine or sulfamethoxazole) are sometimes mixed with the drug trimethoprim, which acts against dihydrofolate reductase. As of 2013 Ireland is the largest exporter worldwide of sulfonamides, accounting for approximately 32% of total exports. [16]
This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name. If an antibiotic is a combination drug, both ingredients will be listed.
Sulfamethoxazole; Sulfamoxole; Sulfanitran; Long-acting. Sulfadimethoxine; ... A history of antibiotics This page was last edited on 3 January 2025, at 18:37 (UTC). ...
It combines isoniazid, pyridoxine, sulfamethoxazole, and trimethoprim. [1] Specifically it is used to prevent tuberculosis , toxoplasmosis , pneumonia , malaria , and isosporiasis . [ 2 ] It is taken by mouth .
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