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Signs of folate deficiency anemia most of the time are subtle. [4] Anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate deficiency in adults. [1] Folate deficiency anemia may result in feeling tired, weakness, changes to the color of the skin or hair, open sores on the mouth, shortness of breath, palpitations, lightheadedness, cold hands and feet, headaches, easy bleeding ...
Folate deficiency may lead to glossitis, diarrhea, depression, confusion, anemia, and fetal neural tube and brain defects. [98] Other symptoms include fatigue, gray hair, mouth sores, poor growth, and swollen tongue. [111] Folate deficiency is diagnosed by analyzing a complete blood count (CBC) and plasma vitamin B 12 and folate levels.
Folate deficiency (vitamin B9 deficiency) can cause glossitis, along with macrocytic anemia, thrombocytopenia, leukopenia, diarrhea, fatigue and possibly neurological signs. [7] Apart from pernicious anemia discussed above, any other cause of vitamin B12 deficiency can cause glossitis, which tends to be painful, smooth and shiny. [7]
Deficiency isn't common, but can produce some scary side effects when it does happen. Lack of vitamin B12 can cause megaloblastic anemia —a condition characterized by larger than normal red ...
Causes of vitamin B12 deficiency. There are a few reasons why someone might develop a vitamin B12 deficiency. Following a vegan diet for years is a big one, says Deborah Cohen, ...
Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [ 2 ] [ 8 ] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.
For determination of cause, further patient history, testing, and empirical therapy may be clinically indicated. A measurement of methylmalonic acid (methylmalonate) can provide an indirect method for partially differentiating Vitamin B 12 and folate deficiencies. The level of methylmalonic acid is not elevated in folic acid deficiency.
As vitamins go, vitamin B12 is a pretty important one. Vitamin B12 has a broad range of roles in our body -- from helping to make DNA and transport iron throughout our systems to protecting our ...