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Diabetic nephropathy is the most common cause of end-stage renal disease and is a serious complication that affects approximately one quarter of adults with diabetes in the United States. [ 13 ] [ 14 ] Affected individuals with end-stage kidney disease often require hemodialysis and eventually kidney transplantation to replace the failed kidney ...
Diabetic nephropathy is a progressive kidney disease caused by angiopathy of the capillaries in the glomeruli. It is characterized by nephrotic syndrome and diffuse scarring of the glomeruli. It is particularly associated with poorly managed diabetes mellitus and is a primary reason for dialysis in many developed countries.
Most young Type 1 diabetic patients experience glomerular hyperfiltration, a typical functional deviation in insulin-dependent diabetes mellitus. [4] A meta-analysis of research done on Type 1 diabetic subjects found that people with glomerular hyperfiltration have a higher chance of developing albuminuria and seeing their diabetic nephropathy worsen. [5]
Persons with nephrogenic diabetes insipidus must consume enough fluids to equal the amount of urine produced. Any underlying cause such as high blood calcium must be corrected to treat nephrogenic diabetes insipidus. The first line of treatment is hydrochlorothiazide and amiloride. [10] Patients may also consider a low-salt and low-protein diet.
Microscopic image of diabetic glomerulosclerosis, the main cause of nephrotic syndrome in adults. Specialty: Nephrology: Symptoms: Swelling, weight gain, feeling tired, foamy urine [1] Complications: Blood clots, infections, high blood pressure [1] Causes: Focal segmental glomerulosclerosis, membranous nephropathy, minimal change disease ...
The most compelling evidence for the treatment of nephropathy has been found: This combination therapy partially reversed the proteinuria and also exhibited a renoprotective effect in patients with diabetic nephropathy, [70] and pediatric IgA nephropathy. [77]
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