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Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.
Helen Mason is a British endocrinologist who specialises in reproductive endocrinology and is deputy head of Biomedical Sciences at St. Georges (University of London).She graduated from Aston University and Imperial College London, and is now a director of PCOS UK, which provides support for health-care professionals dealing with polycystic ovary syndrome. [1]
Clomiphene is initiated for use in patients with polycystic ovary syndrome, psychogenic amenorrhea, post-oral contraceptive amenorrhea, and secondary amenorrhea of unidentified cause. [14] Serum estrogen should be measured prior to therapy which rules out primary pituitary or ovarian failure, endometrial carcinoma, hyperprolactinaemia. [14]
It plays a central role in the multiple imbalances and dysfunctions of polycystic ovary syndrome. During the first two years after menarche 50% of the menstrual cycles could be anovulatory cycles. It is in fact possible to restore ovulation using appropriate medication, and ovulation is successfully restored in approximately 90% of cases.
If the egg fails to release from the follicle in the ovary an ovarian cyst may form. Small ovarian cysts are common in healthy women. Some women have more follicles than usual (polycystic ovary syndrome), which inhibits the follicles to grow normally and this will cause cycle irregularities. Various types of ovarian diseases exist.
In vitro maturation is an assistive reproductive technique typically used in patients with fertility issues including polycystic ovary syndrome (PCOS), high antral follicle counts and ovarian hyper-responsiveness.
The word “polycystic” in polycystic ovary syndrome refers to the development of multiple cysts on a woman’s ovaries. These result from follicles in the ovaries that fail to release eggs ...
Not all women with PCOS have difficulty becoming pregnant. For those who do, anovulation is a common cause. The mechanism of this anovulation is uncertain, but there is evidence of arrested antral follicle development, which, in turn, may be caused by abnormal interaction of insulin and luteinizing hormone (LH) on granulosa cells.
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