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MCF-7 Cells. MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [2]
MMTV-PyMT is the model of breast cancer metastasis, in which MMTV-LTR is used to drive the expression of mammary gland specific polyomavirus middle T-antigen, leading to a rapid development of highly metastatic tumors. [45] MMTV-PyMT is the most commonly used model for the study of mammary tumor progression and metastasis.
MDA-MB-468 is a cell line that was isolated from a 51-year-old female human in 1977, and is commonly used in breast cancer research. MDA-MB-468 cells were extracted from a pleural effusion of mammary gland and breast tissues, and have proven useful for the study of metastasis, migration, and breast cancer proliferation.
A former Playboy model killed herself and her 7-year-old son after jumping from a hotel in Midtown New York City on Friday morning. The New York Post reports that 47-year-old Stephanie Adams ...
Oklahoma death row inmate, Kevin Ray Underwood, 44, is set to be executed Thursday, 18 years after he killed 10-year-old neighbor Jamie Rose Bolin.
The death rate was 19.9 per 100,000 women per year. These rates are age-adjusted and based on 2014–2018 cases and 2015–2019 deaths. Approximately 12.9 percent of women will be diagnosed with female breast cancer at some point during their lifetime, based on 2016–2018 data.
Kreskin (aka The Amazing Kreskin), the renowned mentalist who had his own TV programs in the 1970s, has died. He was 89. Kreskin’s family announced the news in a statement posted on social media ...
3815 16590 Ensembl ENSG00000157404 ENSMUSG00000005672 UniProt P10721 P05532 RefSeq (mRNA) NM_000222 NM_001093772 NM_001122733 NM_021099 RefSeq (protein) NP_000213 NP_001087241 NP_001116205 NP_066922 Location (UCSC) Chr 4: 54.66 – 54.74 Mb Chr 5: 75.74 – 75.82 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase ...