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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity. [4] [5]
Fat mass and obesity-associated protein, also known as alpha-ketoglutarate-dependent dioxygenase FTO, is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. As one homolog in the AlkB family proteins, it is the first messenger RNA (mRNA) demethylase that has been identified. [ 5 ]
Monogenic obesity is excess weight caused by a mutation in a single gene, as opposed to syndromic obesity not tied to a single gene variation and most obesity, which is caused by multiple genetic and environmental risk factors. Monogenetic obesity mostly affects the hypothalamus and leptin–melanocortin system (see hypothalamic obesity ...
An important link between genetics and obesity has just been discovered. Researchers from the University of British Columbia say by silencing a gene that codes for a certain protein, they cut fat ...
Or at least the genes they passed along to you. Quite a few research papers published recently have shown that mutations in genes can control your appetite and your ability to burn You can now ...
The study shows that a new test that assigns a genetic risk score may be able to help people figure out whether they are likely to be successful on injected weight loss medications.
The main feature of this hypothesis is that the current pattern of obesity does not suggest that obesity has been under strong positive selection for a protracted period of time. It is argued instead that the obesity comes about because of genetic drift in the genes controlling the upper limit on our body fatness. Such drift may have started ...
It affects about one in five children and two out of ... Risk Factors for Obesity. Obesity risk factors can be genetic or environmental — the latter has to do with lifestyle choices and things ...