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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution; although, only in a few cases are genes the primary cause of obesity. [4] [5]
Childhood obesity is often the result of an interplay between many genetic and environmental factors. Polymorphisms in various genes controlling appetite and metabolism predispose individuals to obesity when sufficient calories are present. Over 200 genes affect weight by determining activity level, food preferences, body type, and metabolism. [36]
In medicine, genetic susceptibility to a disease refers to a genetic predisposition to a health problem, [1] which may eventually be triggered by particular environmental or lifestyle factors, such as tobacco smoking or diet. Genetic testing is able to identify individuals who are genetically predisposed to certain diseases.
[9] [10] [11] Phenotypes found to be largely environmentally determined in humans include personality, height, and weight. [ 12 ] [ 10 ] [ 13 ] [ 14 ] Twin studies have shown that more than half of the variation in a few major aspects of personality are environmentally determined, and that environmental factors even affect traits like immune ...
[21] [22] Other research also shows that type 2 diabetes can cause obesity as an effect of the changes in metabolism and other deranged cell behavior attendant on insulin resistance. [23] However, environmental factors (almost certainly diet and weight) play a large part in the development of type 2 diabetes in addition to any genetic component.
This genetic condition refers to an abnormally developed hypothalamus, which can affect the secretion of pituitary hormones. Affected patients typically have an underdeveloped sense of smell ...
Genetic effects are broadly divided into two categories: additive and non-additive. Additive genetic effects occur where expression of more than one gene contributes to phenotype (or where alleles of a heterozygous gene both contribute), and the phenotypic expression of these gene(s) can be said to be the sum of these contributions.
Lack of sleep affects your health in several ways — it can even affect your ability to lose weight. When you lose out on sleep, your weight management journey gets out of whack. So, how does ...