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Viagra (Sildenafil): Uses, Benefits and Side Effects. This article was reviewed by Kelly Brown MD, MBA.. Whether you’re a senior in high school or a senior-living resident, you’ve likely heard ...
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]
This story was reviewed by Mike Bohl, MD. In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina (chest pain) from heart disease.
Alcohol, being a diuretic, can cause a person to urinate more frequently, resulting in dehydration. [84] Dehydration reduces the volume of blood in the body, consequently decreasing blood flow towards the penis [ 84 ] Additionally, dehydration also increases angiotensin levels in the body, which is a hormone associated with erectile dysfunction.
For example, a study published in the journal, which involved more than 300 men with ED, found that men who consumed above-average amounts of alcohol were more likely to develop headaches and ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.
In clinical trials of Viagra, more than 82 percent of men with ED reported an improvement in their climaxes after using Viagra at a dosage of 100mg (the highest dosage prescribed for ED).