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Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.
Although anxiety can temporarily increase as a withdrawal symptom, there is evidence that a reduction or withdrawal from benzodiazepines can lead to a reduction of anxiety symptoms in the long run. [4] [5] Due to these increasing physical and mental symptoms from long-term use of benzodiazepines, slow withdrawal is recommended for long-term users.
Anti-epileptic drugs, benzodiazepines such as clonazepam in particular, should be reduced in dose slowly and gradually when discontinuing the drug to mitigate withdrawal effects. [67] Carbamazepine has been tested in the treatment of clonazepam withdrawal but was found to be ineffective in preventing clonazepam withdrawal-induced status ...
According to Endo, Inc.’s recall, the Clonazepam being recalled is in cartons containing 60 tablets that are packed into 10 blister strips, containing six tablets each.
Tablets of the drug clonazepam, the generic name for Klonopin, which is used to treat epilepsy, panic disorder and muscle spasms, have been recalled for incorrect labeling that could inadvertently ...
The anxiety-reducing drug, Clonazepam, has been recalled after a potentially "life-threatening" label mix-up, the Food and Drug Administration (FDA) said. According to a release from the federal ...
Withdrawal symptoms can persist for quite some time after discontinuing benzodiazepines. Some common protracted withdrawal symptoms include anxiety, depression, insomnia, and physical symptoms such as gastrointestinal, neurologic, and musculoskeletal effects. The protracted withdrawal state may still occur despite slow titration of dosage.
In the UK, both clobazam and clonazepam are second-line choices for treating many forms of epilepsy. [54] Clobazam also has a useful role for very short-term seizure prophylaxis and in catamenial epilepsy. [53] Discontinuation after long-term use in epilepsy requires additional caution because of the risks of rebound seizures.