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  2. Benadryl for Dogs? A Vet Explains How Much You Should Give - AOL

    www.aol.com/benadryl-dogs-vet-explains-much...

    One study of a dog suffering from a toxic dose found that it was probably 111 milligrams per kilogram, or about 100 times the normal dose (3). Other reports list the lethal dose (LD50) at 24 to 30 ...

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    A naturally occurring inhibitor of factor Xa was reported in 1971 by Spellman et al. from the dog hookworm. [15] In 1987, Tuszynski et al. discovered antistasin, which was isolated from the extracts of the Mexican leech, Haementeria officinalis.

  4. 7 Alternatives to Chemotherapy for Lymphoma in Dogs - AOL

    www.aol.com/7-alternatives-chemotherapy-lymphoma...

    1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...

  5. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  6. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    In dog testing, this compound with a carboxamide group called 13F, showed a great pharmacokinetical profile, a low clearance and adequate half-life and volume of distribution. Due to the success of finding a stabilizing group, SAR research for S1 binding moiety (p-methoxyphenyl) was discontinued.

  7. Skin conditions in dogs: Symptoms, causes, and how to help - AOL

    www.aol.com/skin-conditions-dogs-symptoms-causes...

    The dog then causes further trauma to the skin by itching and rubbing at the area, leading to a secondary bacterial infection." Acute moist dermatitis: Symptoms A patch of moist, inflamed skin ...

  8. Dog health - Wikipedia

    en.wikipedia.org/wiki/Dog_health

    The lethal dose for 50% of dogs is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg. [38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended ...

  9. 32 practical steps you can take to help your dog lose weight

    www.aol.com/32-practical-steps-help-dog...

    Here are 32 ways to help your dog lose weight. ... Many ultra-processed dog foods are packed with carb-based fillers, most of which come from cereal grains. Focusing on lower carb, whole, fresh ...

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