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  2. Diabetes in dogs - Wikipedia

    en.wikipedia.org/wiki/Diabetes_in_dogs

    The aim is to keep the blood glucose values in an acceptable range. The commonly recommended dosing method is by "starting low and going slow" as indicated for people with diabetes. [55] During the initial process of regulation and periodically thereafter, the effectiveness of the insulin dose at controlling blood glucose is evaluated. [56]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    A naturally occurring inhibitor of factor Xa was reported in 1971 by Spellman et al. from the dog hookworm. [15] In 1987, Tuszynski et al. discovered antistasin, which was isolated from the extracts of the Mexican leech, Haementeria officinalis.

  4. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  5. FDA Issues Urgent Warning on Dangers of Common Dog Medication

    www.aol.com/fda-issues-urgent-warning-dangers...

    The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...

  6. Benadryl for Dogs? A Vet Explains How Much You Should Give - AOL

    www.aol.com/benadryl-dogs-vet-explains-much...

    The standard dose is about the same, 1–2 mg per pound of body weight, but a slightly higher dose of 3 mg per pound may be helpful with some dogs. (This is higher than the dose recommended, but ...

  7. Why is my dog peeing so much? Vet explains the causes for ...

    www.aol.com/why-dog-peeing-much-vet-120000893.html

    Here are some guidelines to follow: Puppies You can expect even more frequent urination during potty training as they gradually learn to control their urges to pee.

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  9. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

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