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Arsphenamine, also known as Salvarsan or compound 606, is an antibiotic drug that was introduced at the beginning of the 1910s as the first effective treatment for the deadly infectious diseases syphilis, relapsing fever, and African trypanosomiasis. [2] [3] This organoarsenic compound was the first modern antimicrobial agent. [4]
All RMPs for COVID‑19 vaccines will be published on the EMA's website. [136] The EMA published guidance for developers of potential COVID‑19 vaccines on the clinical evidence to include in marketing authorization applications. [137] In November 2020, the CHMP started a rolling review of the Moderna vaccine for COVID‑19 known as mRNA-1273 ...
1911 – Arsphenamine, also Salvarsan [1] 1912 – Neosalvarsan; 1935 – Prontosil (an oral precursor to sulfanilamide), the first sulfonamide; 1936 – Sulfanilamide; 1938 – Sulfapyridine (M&B 693) 1939 – sulfacetamide; 1940 – sulfamethizole; 1942 – benzylpenicillin, the first penicillin; 1942 – gramicidin S, the first peptide ...
One of the most notable scientific papers that first popularized hydroxychloroquine as a COVID-19 treatment was retracted from its journal due to ethical and methodological issues. Retractions in ...
A morning aerial photo taken on March 30, 2020 shows deserted streets and the Colosseum monument in Rome during the country's lockdown aimed at curbing the spread of the COVID-19 infection, caused ...
Both Salvarsan and Neosalvarsan were developed in the laboratory of Paul Ehrlich in Frankfurt, Germany. Their discoveries were the result of the first organized team effort to optimize the biological activity of a lead compound through systematic chemical modifications. [1] This scheme is the basis for most modern pharmaceutical research.
A new study shows that the XBB vaccine can protect against several emerging variants.
This was the first agent with a specific therapeutic effect to be created on the basis of theoretical considerations. Salvarsan proved to be amazingly effective, particularly when compared with the conventional therapy of mercury salts. Manufactured by Hoechst AG, Salvarsan became the most widely prescribed drug in the world.
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