Search results
Results from the WOW.Com Content Network
High-altitude pulmonary edema (HAPE) is a life-threatening form of non-cardiogenic pulmonary edema that occurs in otherwise healthy people at altitudes typically above 2,500 meters (8,200 ft). [2] HAPE is a severe presentation of altitude sickness .
The medical problems that are direct consequence of high altitude are caused by the low inspired partial pressure of oxygen, which is caused by the reduced atmospheric pressure, and the constant gas fraction of oxygen in atmospheric air over the range in which humans can survive. [1]
Altitude sickness, the mildest form being acute mountain sickness (AMS), is a harmful effect of high altitude, caused by rapid exposure to low amounts of oxygen at high elevation. [ 1 ] [ 2 ] [ 3 ] People's bodies can respond to high altitude in different ways.
Sildenafil is used as a preventive treatment for altitude-induced pulmonary edema and pulmonary hypertension. [ 38 ] [ 39 ] Sildenafil's mechanism of action is via phosphodiesterase inhibition which raises cGMP, resulting in pulmonary arterial vasodilation and inhibition of smooth muscle cell proliferation and indirectly fluid formation in the ...
This response can be attributed to genetic factors, but the development of the resistance to acute hypoxia is highly affected by when the individual is exposed to high altitude; [20] while genetic factors play an indefinite role in a person's HVR, because long term migrants do not show reduction in their reactions of high altitude even after ...
An IHT session consists of an interval of several minutes breathing hypoxic (low oxygen) air, alternated with intervals breathing ambient (normoxic) or hyperoxic air. The procedure may be repeated several times in variable-length sessions per day, depending on a physician's prescription or a manufacturer's protocol. [ 1 ]
High altitude breathing apparatus is a breathing apparatus which allows a person to breathe more effectively at an altitude where the partial pressure of oxygen in the ambient atmospheric air is insufficient for the task or to sustain consciousness or human life over the long or short term.
Hypobaric chamber at the Biopol'H, in Catalonia (), used with patients and athletes who need treatment or training with reduced atmospheric pressure. A hypobaric chamber, or altitude chamber, is a chamber used during aerospace or high terrestrial altitude research or training to simulate the effects of high altitude on the human body, especially hypoxia (low oxygen) and hypobaria (low ambient ...