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You may have also heard of ketamine therapy, which uses ketamine, a drug that was originally used as an animal anesthetic, administered in a clinical setting to improve mental health symptoms.
Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
Dennis S. Charney is an American biological psychiatrist and researcher, with expertise in the neurobiology and treatment of mood and anxiety disorders. [1] He is the author of Neurobiology of Mental Illness, The Physician's Guide to Depression and Bipolar Disorders and Molecular Biology for the Clinician, as well as the author of over 600 original papers and chapters.
“Ketamine treatment is associated with an altered state of thinking, a psychedelic-like state of thinking, for a short period of time. There’s a substantial amount of evidence that that is ...
Evidence is growing for the use of atypical psychedelics such as ketamine for treating depression in terminally ill patients, with repeated IV administration having the most therapeutic effect. [62] These studies did not have any patients experience any serious adverse effects; however, ketamine-induced ulcerative cystitis is a concern for ...
Physicians also urged people not to write off ketamine for medical treatment in light of the tragedy. When doctors turn to ketamine for patients with depression, “these are patients who might ...
“Patients say, ‘This changed my life,’” said Mike Dow, a psychotherapist at a Field Trip clinic in Los Angeles. It’s unclear how ketamine works precisely in the brain.
After the publication of the NIH-run antidepressant clinical trial, clinics began opening in which the intravenous ketamine is given for depression. [5] [6] This practice is an off label use of IV ketamine in the United States, though the intranasal version of esketamine has been approved by the FDA for treatment of depression [5] [7] In 2015 there were about 60 such clinics in the US; the ...