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Peeling skin syndrome in the legs and feet. Peeling skin syndrome (also known as acral peeling skin syndrome, continual peeling skin syndrome, familial continual skin peeling, idiopathic deciduous skin, and keratolysis exfoliativa congenita [1]) is an autosomal recessive disorder characterized by lifelong peeling of the stratum corneum, and may be associated with pruritus, short stature, and ...
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
The hands and feet usually are the first to show signs of the disease but the disease can advance to other parts of the body. Signs of the disease include thickening of the skin, on hands and soles of feet, which can turn red in color. [6] There currently is no cure and treatment is limited, but Acitretin can be used in severe cases. [7]
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Keratolysis exfoliativa (also known as"lamellar dyshidrosis", [1] "recurrent focal palmar peeling", [2] "recurrent palmar peeling" [1]: 212 [2]) is a sometimes harmless, sometimes painful skin condition that can affect the focal surface of the fingers and/or the palm or soles of the feet.
TGM5 mutations can cause acral peeling skin syndrome, an autosomal recessive genodermatosis characterized by the shedding of the outer epidermis. [1] [2] In the acral form, the dorsa of the hands and feet are predominantly affected. Ultrastructural analysis has revealed tissue separation at the junction between the granular cells and the ...
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]
The hands of the black male were extended directly above his head as his upper torso was parallel with the ground. They continued to walk the male down the sidewalk and towards an open door of the ...