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  2. Bicarbonate - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate

    The bicarbonate ion (hydrogencarbonate ion) is an anion with the empirical formula HCO − 3 and a molecular mass of 61.01 daltons; it consists of one central carbon atom surrounded by three oxygen atoms in a trigonal planar arrangement, with a hydrogen atom attached to one of the oxygens. It is isoelectronic with nitric acid HNO 3.

  3. Ductal cells - Wikipedia

    en.wikipedia.org/wiki/Ductal_cells

    While ductal cells are a minor type of cell in the adult pancreas, they have a critical function besides making the network that transfers enzymes from acini to the digestive tract. The primary function of pancreas ductal cells is to secrete a bicarbonate-rich, isotonic fluid. This fluid washes away the inactive form of digestive enzymes in the ...

  4. Bicarbonate buffer system - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate_buffer_system

    Most of the carbonic acid then dissociates to bicarbonate and hydrogen ions. The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of carbonic acid (H 2 CO 3), bicarbonate ion (HCO − 3), and carbon dioxide (CO 2) in order to maintain pH in the blood and duodenum, among other tissues, to support proper ...

  5. Pancreatic juice - Wikipedia

    en.wikipedia.org/wiki/Pancreatic_juice

    The pancreas also receives autonomic innervation. The blood flow into pancreas is regulated by sympathetic nerve fibers, while parasympathetic neurons stimulate the activity of acinar and centroacinar cells. Pancreatic secretion is an aqueous solution of bicarbonate originating from the duct cells and enzymes originating from the acinar cells.

  6. Centroacinar cell - Wikipedia

    en.wikipedia.org/wiki/Centroacinar_cell

    The exocrine pancreas is one of two compartments that include digestive-acting acinar cells and duct cells.They represent an extension of the intercalated duct into each pancreatic acinus. [1] These cells are commonly known as duct cells , and secrete an aqueous bicarbonate solution under stimulation by the hormone secretin .

  7. Alkaline tide - Wikipedia

    en.wikipedia.org/wiki/Alkaline_tide

    The alkaline tide is neutralised by a secretion of H + into the blood during HCO 3 − secretion in the pancreas. [2] Postprandial (i.e., after a meal) alkaline tide lasts until the acids in food absorbed in the small intestine reunite with the bicarbonate that was produced when the food was in the stomach. Thus, alkaline tide is self-limited ...

  8. Human digestive system - Wikipedia

    en.wikipedia.org/wiki/Human_digestive_system

    Aqueous pancreatic secretions from pancreatic duct cells contain bicarbonate ions which are alkaline and help with the bile to neutralise the acidic chyme that is churned out by the stomach. The pancreas is also the main source of enzymes for the digestion of fats and proteins.

  9. Parietal cell - Wikipedia

    en.wikipedia.org/wiki/Parietal_cell

    Water is a very minor source of hydrogen ions in comparison to carbonic acid. Carbonic acid is formed from carbon dioxide and water by carbonic anhydrase. The bicarbonate ion (HCO 3 −) is exchanged for a chloride ion (Cl −) on the basal side of the cell and the bicarbonate diffuses into the venous blood, leading to an alkaline tide phenomenon.