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Most individuals with G6PD deficiency are asymptomatic.When it induces hemolysis, it is usually is short-lived. [5]Most people who develop symptoms are male, due to the X-linked pattern of inheritance, but female carriers can be affected due to unfavorable lyonization or skewed X-inactivation, where random inactivation of an X-chromosome in certain cells creates a population of G6PD-deficient ...
G6PD converts G6P into 6-phosphoglucono-δ-lactone and is the rate-limiting enzyme of the pentose phosphate pathway. Thus, regulation of G6PD has downstream consequences for the activity of the rest of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is stimulated by its substrate G6P.
These, together with the National Capital Region, are further subdivided into cities (Filipino: lungsod) and municipalities (Filipino: bayan). Cities are classified under the Local Government Code of 1991 (Republic Act No. 7160) into three categories: highly urbanized cities, independent component cities, and component cities.
People suffering from 6PGD or G6PD deficiency (or both) are at risk of hemolytic anemia in states of oxidative stress. Oxidative stress can result from infection and from chemical exposure to medication and certain foods. Broad beans, e.g., fava beans, contain high levels of vicine, divicine, convicine and isouramil, all of which are oxidants.
For instance, 1st class cities have an income of ₱ 400 million or more, while 6th class cities earn less than ₱ 80 million in a four-year period. Each city is governed by both the Local Government Code of 1991 [2] and the city's own municipal charter, under the laws of the Philippines.
The Philippines has three metropolitan areas officially recognized by the National Economic and Development Authority (NEDA) due to their prominence, population, size, and economy: Manila, Cebu, and Davao. [1] [2] The most populous is Metro Manila, which comprises the City of Manila, 15 neighboring cities, and a
This is a list of Philippine provinces sorted by population as of the 2020 census, which was conducted by the Philippine Statistics Authority (PSA). Population of provinces in this list includes population of highly urbanized cities, which are administratively independent of the province.
A city (Filipino: lungsod or siyudad) is one of the units of local government in the Philippines.All Philippine cities are chartered cities (Filipino: nakakartang lungsod), whose existence as corporate and administrative entities is governed by their own specific municipal charters in addition to the Local Government Code of 1991, which specifies their administrative structure and powers.