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Alendronic acid is indicated for the treatment and prevention of osteoporosis in postmenopausal women; [3] the treatment to increase bone mass in men with osteoporosis; [3] the treatment of glucocorticoid-induced osteoporosis; [3] and the treatment of Paget's disease of bone.
Omega−3-carboxylic acids are used in addition to changes in diet to reduce triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. [6]Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects ...
Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses, the effects can be significant (from 20% to 35% and even up to 45% in individuals with levels greater than 500 mg/dL).
To illustrate the amounts of EPA and DHA in supplements, a softgel capsule containing fish oil derived from pollock might contain a total of 642 mg of total fish oil, of which 584 mg are omega−3 fatty acids, with 377 mg EPA and 158 mg DHA. 3 That same company's salmon oil softgel contains 1008 mg of total fish oil, of which 295 mg are omega ...
Ethyl eicosapentaenoic acid is a prescription medication in the US, but it closely resembles other marine based omega−3 dietary supplements. Evidence suggests that these supplements are able to reduce cardiovascular disease, [21] and premature death. [22] These effects may not carry over in other populations such as people who have diabetes.
A 2019 review found that omega−3 supplements have no effect on prevention and treatment of type 2 diabetes. [168] [169] A 2021 meta-analysis found that supplementation with omega−3 had positive effects on diabetes biomarkers, such as fasting blood glucose and insulin resistance. [170]
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