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Tazarotene, sold under the brand name Tazorac, among others, is a third-generation prescription topical retinoid. [2] [3] It is primarily used for the treatment of plaque psoriasis and acne. [4] Tazarotene is also used as a therapeutic for photoaged and photodamaged skin. [4] It is a member of the acetylenic class of retinoids. [4]
[8] [23] The ointment and topical suspension formulation (Daivobet) were also approved in 2010 by the European Medicines Agency for the treatment of plaque psoriasis where it is possible to use a topical medication (ointment), and for the treatment of scalp psoriasis or mild to moderate plaque psoriasis on the body (topical suspension). [24]
As psoriasis is typically thought to be partially driven by Th1/Th17 inflammatory cytokines, [12] calcipotriol treatment at appropriate concentrations may alleviate psoriasis symptoms by repressing Th1/Th17 inflammation through TSLP production, which is linked to a Th2 response. However, it is important to note that this has not yet been confirmed.
From topical creams and phototherapy to steroids and newer injectables called biologics, here's how to choose the right treatment for you.
Many products sold illegally have higher concentrations of clobetasol propionate than is permitted for prescription drugs. [19] Clobetasol 0.05% is considered a member of the "super-high potency" group of topical corticosteroids out of seven total groups in the United States classification system of topical corticosteroids. [20] [9]
Desonide is a prescription topical treatment for redness, swelling, itching, and discomfort of various skin conditions. Regardless of the vehicle used, desonide is applied 2 to 3 times a day, at the same times each day. Skin conditions typically improve in the first two weeks of treatment.
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