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Throughout her tenure at the University of Rochester, Gorbunova's research team continued to focus on the naked mole rat as a key to understanding cancer resistance among animals. In 2013, Gorbunova and Seluanov identified high molecular weight hyaluronan as the key mediator of cancer resistance in the naked mole rat. [9]
The naked mole-rat (Heterocephalus glaber), also known as the sand puppy, [6] is a burrowing rodent native to the Horn of Africa and parts of Kenya, notably in Somali regions. It is closely related to the blesmols and is the only species in the genus Heterocephalus .
Rochelle Buffenstein is an American comparative biologist currently working as Research Professor at the University of Illinois Chicago.Previously, she was a senior principal investigator at Calico Life Sciences, an Alphabet, Inc. funded research and development company investigating the biology that controls aging and lifespan where she used the extraordinarily long-lived cancer resistant ...
It may look like a whiskered cocktail sausage, but the naked mole rat's incredible biology may one day improve countless lives. Meet the naked mole-rat: impervious to pain and cancer, and lives ...
Cells of naked mole rats, a species in which cancer has never observed, show hypersensitivity to contact inhibition. [8] This finding may provide a clue to cancer resistance. Furthermore, recent studies have further revealed some mechanisms of contact inhibition of proliferation and its potential implications in cancer therapy.
Heterocephalus glaber (Naked mole-rat), studied for their characteristic pain insensitivity, thermoregulation, cancer resistance, eusociality, and longevity. Nothobranchius furzeri, is studied because of their extreme short-lifespan in research on aging, disease and evolution.
Reference 36 is clear that of the naked mole rats present in the 30 year study, over 60% were still alive after it's conclusion. This quote is from the same source: "This survival estimate suggested the naked mole-rat maximal lifespan to be far longer than the current 30 year published record (Lewis and Buffenstein, 2016; Buffenstein, 2008)."
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