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Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella, and the causative agent of pertussis or whooping cough. Its virulence factors include pertussis toxin , adenylate cyclase toxin , filamentous haemagglutinin , pertactin , fimbria , and tracheal cytotoxin .
Gram-negative bacteria have a thin peptidoglycan layer which does not retain the crystal violet, so when safranin is added during the process, they stain red. The Mycoplasmataceae lack a peptidoglycan layer so do not retain crystal violet or safranin, resulting in no color. The Chlamydiaceae contain an extremely thin peptidoglycan layer ...
Bordetella (/ ˌ b ɔːr d ə ˈ t ɛ l ə /) is a genus of small (0.2 – 0.7 μm), Gram-negative, coccobacilli bacteria of the phylum Pseudomonadota. Bordetella species, with the exception of B. petrii, are obligate aerobes, as well as highly fastidious, or difficult to culture.
Whooping cough (/ ˈ h uː p ɪ ŋ / or / ˈ w uː p ɪ ŋ /), also known as pertussis or the 100-day cough, is a highly contagious, vaccine-preventable bacterial disease. [1] [10] Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. [1]
Aggregatibacter actinomycetemcomitans is a Gram-negative coccobacillus prevalent in subgingival plaques. Acinetobacter strains may grow on solid media as coccobacilli. Bordetella pertussis is a Gram-negative coccobacillus responsible for causing whooping cough. Yersinia pestis, the bacterium that causes plague, is also coccobacillus. [26]
Medical Microbiology, 4th edition, [1] states that Regan-Lowe medium [2] (containing charcoal, blood, and antibiotic) has replaced Bordet–Gengou medium as the medium of choice for routine Bordetella pertussis incubation. Bordetella bacteria were difficult to culture; Jules Bordet and Octave Gengou invented the first version to isolate the ...
Bordetella bronchiseptica is a small, gram-negative, rod-shaped bacterium of the genus Bordetella. [1] It can cause infectious bronchitis in dogs and other animals, [ 2 ] but rarely infects humans. [ 3 ]
Pertussis toxin (PT) is a protein-based AB 5-type exotoxin produced by the bacterium Bordetella pertussis, [2] which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. [ 3 ]