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The United States Medical Licensing Examination (USMLE) Step 1 is a standardized test that assesses a medical student's knowledge of basic science concepts and their application to clinical medicine. The exam is one of three components required for medical licensure in the United States and is typically taken by students after their second year ...
CUSHING: . Central obesity/ Cervical fat pads/ Collagen fiber weakness/ Comedones (acne) . Urinary free corisol and glucose increase . Striae/ Suppressed immunity . Hypercortisolism/ Hypertension/ Hyperglycemia/ Hirsutism
Pathophysiology (or physiopathology) is a branch of study, at the intersection of pathology and physiology, concerning disordered physiological processes that cause, result from, or are otherwise associated with a disease or injury.
A summary of the pathophysiology of a type 1 hypersensitivity reaction. Type I hypersensitivity can be further classified into immediate and late-phase reactions. Within minutes of exposure to an antigen, the immediate hypersensitivity occurs, releasing histamines and lipid mediators which are responsible for the initial allergic reaction response.
In cell biology and pathophysiology, cellular adaptation refers to changes made by a cell in response to adverse or varying environmental changes. The adaptation may be physiologic (normal) or pathologic (abnormal). Morphological adaptations observed at the cellular level include atrophy, hypertrophy, hyperplasia, and metaplasia. [1]
Clinical physiology is an academic discipline within the medical sciences and a clinical medical specialty for physicians in the health care systems of Sweden, [1] Denmark, Portugal [2] and Finland. Clinical physiology is characterized as a branch of physiology that uses a functional approach to understand the pathophysiology of a disease. [3]
In terms of cause, almost any condition that involves ischemia can lead to renal papillary necrosis. A mnemonic for the causes of renal papillary necrosis is POSTCARDS: pyelonephritis, obstruction of the urogenital tract, sickle cell disease, tuberculosis, cirrhosis of the liver, analgesia/alcohol use disorder, renal vein thrombosis, diabetes mellitus, and systemic vasculitis. [3]
Myoglobinuria pathophysiology consists of a series of metabolic actions in which damage to muscle cells affect calcium mechanisms, thereby increasing free ionized calcium in the cytoplasm of the myocytes (concurrently decreasing free ionized calcium in the bloodstream). This, in turn, affects several intracellular enzymes that are calcium ...