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Thromboembolism is a condition in which a blood clot breaks off from its original site and travels through the bloodstream (as an embolus) to obstruct a blood vessel, causing tissue ischemia and organ damage. Thromboembolism can affect both the venous and arterial systems, with different clinical manifestations and management strategies.
A thrombus (pl. thrombi), colloquially called a blood clot, is the final product of the blood coagulation step in hemostasis. There are two components to a thrombus: aggregated platelets and red blood cells that form a plug, and a mesh of cross-linked fibrin protein. The substance making up a thrombus is sometimes called cruor.
There are four mechanisms by which poor blood flow occurs: a blood clot from elsewhere getting lodged in an artery, a new blood clot forming in an artery, a blood clot forming in the superior mesenteric vein, and insufficient blood flow due to low blood pressure or spasms of arteries. [3] [6] Chronic disease is a risk factor for acute disease. [7]
Different types of blood clots bring different kinds of symptoms. Doctors explain what you might experience if you have a blood clot. What a Blood Clot Feels Like, According to Doctors
Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an embolus. [1] [2] Thrombosis may occur in veins (venous thrombosis) or in arteries (arterial thrombosis).
Small amounts of bleeding over a long time may cause iron-deficiency anemia resulting in feeling tired or heart-related chest pain. [1] Other symptoms may include abdominal pain, shortness of breath, pale skin, or passing out. [1] [9] Sometimes in those with small amounts of bleeding no symptoms may be present. [1]
Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels. [1] Symptoms may include chest pain, shortness of breath, leg pain, problems speaking, or problems moving parts of the body. [1] As clotting factors and platelets are used up, bleeding may occur. [1]
Small blood clots—say, dime- or nickel-sized on your heaviest flow days—may appear during menstruation and that’s not uncommon, especially if you feel fine otherwise and you’re not ...