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Cancer is caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability. [1][2] A minority of cancers are due to inherited genetic mutations. [3] Most cancers are related to environmental, lifestyle, or behavioral exposures. [4]
The most common as of 2018 are lung cancer (1.76 million deaths), colorectal cancer (860,000) stomach cancer (780,000), liver cancer (780,000), and breast cancer (620,000). [2] This makes invasive cancer the leading cause of death in the developed world and the second leading in the developing world . [ 25 ]
The leading cause of liver cancer is cirrhosis due to hepatitis B, hepatitis C, or alcohol. [4] Other causes include aflatoxin, non-alcoholic fatty liver disease and liver flukes. [3] The most common types are HCC, which makes up 80% of cases and intrahepatic cholangiocarcinoma. [3]
“Cancer is the second leading cause of death in the U.S.,” Jamie Koprivnikar, MD, oncologist and hematologist in the Division of Leukemia at the The John Theurer Cancer Center at Hackensack ...
Worldwide, lung cancer is the most diagnosed type of cancer, and the leading cause of cancer death. [95] [96] In 2020, 2.2 million new cases were diagnosed, and 1.8 million people died from lung cancer, representing 18% of all cancer deaths. [3]
Thyroid cancer affects tens of thousands of people per year, and the majority are women. ... Hashimoto's disease is an autoimmune disease that generally causes an underactive thyroid (and rarely ...
In 2011, prostate cancer was the most common form of cancer among males (about 28% of all new cases) and breast cancer the most common in females (also about 28% of all new cases). [citation needed] The leading cause of death in both males and females is lung cancer, which contributes to 26.8% of all cancer deaths.
Colorectal cancer is the second leading cause of cancer-related death worldwide. [176] Transitioning into palliative care and contending with mortality can be a deeply distressing experience for a CRC patient and their loved ones.
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