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SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.
Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. [5] For the prevention of cardiovascular disease, statins are a first-line treatment. [5] It is taken by mouth. [5] Common side effects include joint pain, diarrhea, heartburn, nausea, and muscle pains. [5]
This is known as statin intolerance. A 2021 double-blind multiple crossover randomized controlled trial (RCT) in statin-intolerant patients found that adverse effects, including muscle pain, were similar between atorvastatin and placebo. [88] A smaller double-blind RCT obtained similar results. [89]
For example, you might develop cellulitis – it’s the most common infection that occurs when bacteria breach the skin barrier. An estimated 1 in 503 people, or 0.2%, of the population get this ...
The main symptoms include several kinds of skin rash along with muscle weakness in both upper arms or thighs. [8] Although dermatomyositis is closely related to polymyositis and is sometimes assumed to be a complication of that disease, most patients with dermatomyositis develop skin symptoms before any muscle involvement.
When a stress rash manifests as hives, it looks like raised, itchy bumps on the skin that may be red or pink. Hives can be a collection of individual bumps or connected, making one large bump.
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Arthralgia (from Greek arthro- 'joint' and -algos 'pain') literally means 'joint pain'. [1] [2] Specifically, arthralgia is a symptom of injury, infection, illness (in particular arthritis), or an allergic reaction to medication.