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Vitamin B 12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
"B12" and "Cbl" redirect here. For other uses of B12, see B12 (disambiguation). For the musical group, see Carbon Based Lifeforms. Pharmaceutical compound Vitamin B12 General skeletal formula of cobalamins Stick model of cyanocobalamin (R = CN) based on the crystal structure Clinical data Other names Vitamin B12, vitamin B-12, cobalamin AHFS / Drugs.com Monograph MedlinePlus a605007 License ...
Supplementation with folate can mask vitamin B 12 deficiency. [39] [40] Consuming a vegan diet increases the risk, since Vitamin B 12 is mostly found in food and drinks made from animal products, including eggs and dairy products. Vitamin C deficiency: Deficiency leads to weakness, weight loss and general aches and pains.
Serum vitamin B 12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin , while only 6–20% is binds to transcobalamin ll. [ 2 ] Only transcobalamin ll is "active" and can be used by the body. [ 1 ]
Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer. [9] [5] It is used by mouth, by injection into a muscle, or as a ...
Hydroxocobalamin, also known as vitamin B 12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. [1] As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia.
Hypocalcemia is a medical condition characterized by low calcium levels in the blood serum. [5] The normal range of blood calcium is typically between 2.1–2.6 mmol/L (8.8–10.7 mg/dL, 4.3–5.2 mEq/L), while levels less than 2.1 mmol/L are defined as hypocalcemic.
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