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24 million annually (2019) [ 6] Deaths. 10 million annually (2019) [ 6] Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [ 2][ 7] These contrast with benign tumors, which do not spread. [ 7]
Cancer is caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability. [ 1][ 2] A minority of cancers are due to inherited genetic mutations. [ 3] Most cancers are related to environmental, lifestyle, or behavioral exposures. [ 4]
Lung cancer. Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.
Pancreatic cancer is among the most deadly forms of cancer globally, with one of the lowest survival rates. In 2015, pancreatic cancers of all types resulted in 411,600 deaths globally. [8] Pancreatic cancer is the fifth-most-common cause of death from cancer in the United Kingdom, [19] and the third most-common in the United States. [20]
Deaths. 353,500 (2015) [ 8] Leukemia ( also spelled leukaemia; pronounced / luːˈkiːmiːə / [ 1] loo-KEE-mee-ə) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. [ 9] These blood cells are not fully developed and are called blasts or leukemia cells. [ 2]
Colorectal cancer ( CRC ), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine ). [ 5] Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, abdominal pain and fatigue. [ 9] Most colorectal cancers are due to old ...
341,831 (2020) [ 11] Cervical cancer is a cancer arising from the cervix or in the any layer of the wall of the cervix. [ 2] It is due to the abnormal growth of cells that have the ability to invade or spread to other parts of the body. [ 12] Early on, typically no symptoms are seen. [ 2]
Constitutional Symptoms. Unexplained pain: Pain that persists, has no clear cause, and does not respond to treatment may be a warning sign of many types of cancers. Unexplained night sweats or fever: These may be signs of an immune system cancer. Fever in children rarely points to malignancy, but may merit evaluation.