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Ion channels are located within the membrane of all excitable cells, [ 3] and of many intracellular organelles. They are often described as narrow, water-filled tunnels that allow only ions of a certain size and/or charge to pass through. This characteristic is called selective permeability.
Voltage-gated ion channels have a crucial role in excitable cells such as neuronal and muscle tissues, allowing a rapid and co-ordinated depolarization in response to triggering voltage change. Found along the axon and at the synapse, voltage-gated ion channels directionally propagate electrical signals. Voltage-gated ion-channels are usually ...
These ion channels have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. TRP channels were initially discovered in the so-called "transient receptor potential" mutant (trp-mutant) strain of the fruit fly Drosophila, hence their name (see History of Drosophila TRP channels below). Later, TRP channels ...
Doina and Ion Aldea Teodorovici. Doina and Ion Aldea Teodorovici was a Moldovan musical duo consisting of married couple Doina and Ion Aldea Teodorovici. The group disbanded in 1992, after both members died in a road traffic accident in Coșereni. Today, there is a monument to them there, [1] [2] as well as another in Chișinău.
Voltage-gated sodium channels ( VGSCs ), also known as voltage-dependent sodium channels ( VDSCs ), are a group of voltage-gated ion channels found in the membrane of excitable cells ( e.g., muscle, glial cells, neurons, etc.) with a permeability to the sodium ion Na +. They are the main channels involved in action potential of excitable cells.
Acid-sensing ion channel. Alpha-3 beta-2 nicotinic receptor. Alpha-3 beta-4 nicotinic receptor. Alpha-4 beta-2 nicotinic receptor. Alpha-7 nicotinic receptor. Anion-conducting channelrhodopsin. ASIC5.
The channelome, sometimes called the "ion channelome", is the complete set of ion channels and porins expressed in a biological tissue or organism. It is analogous to the genome , the metabolome (describing metabolites), the proteome (describing general protein expression), and the microbiome .
Small conductance mechanosensitive ion channels (MscS) provide protection against hypo-osmotic shock in bacteria, responding both to stretching of the cell membrane and to membrane depolarization. In eukaryotes, they fulfill a multitude of important functions in addition to osmoregulation. [1] They are present in the membranes of organisms from ...