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  2. Davenport diagram - Wikipedia

    en.wikipedia.org/wiki/Davenport_diagram

    Recall that the relationship represented in a Davenport diagram is a relationship between three variables: P CO 2, bicarbonate concentration and pH.Thus, Fig. 7 can be thought of as a topographical map—that is, a two-dimensional representation of a three-dimensional surface—where each isopleth indicates a different partial pressure or “altitude.”

  3. Bicarbonate buffer system - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate_buffer_system

    The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of carbonic acid (H 2 CO 3), bicarbonate ion (HCO − 3 ), and carbon dioxide (CO 2 ) in order to maintain pH in the blood and duodenum , among other tissues, to support proper metabolic function. [ 1 ]

  4. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acid–base_homeostasis

    An acid-base diagram for human plasma, showing the effects on the plasma pH when P CO 2 in mmHg or Standard Base Excess (SBE) occur in excess or are deficient in the plasma [23] Acid–base imbalance occurs when a significant insult causes the blood pH to shift out of the normal range (7.32 to 7.42 [ 16 ] ).

  5. Chloride shift - Wikipedia

    en.wikipedia.org/wiki/Chloride_shift

    Chloride shift (also known as the Hamburger phenomenon or lineas phenomenon, named after Hartog Jakob Hamburger) is a process which occurs in a cardiovascular system and refers to the exchange of bicarbonate (HCO 3 −) and chloride (Cl −) across the membrane of red blood cells (RBCs). [1]

  6. Acid–base disorder - Wikipedia

    en.wikipedia.org/wiki/Acid–base_disorder

    Acid–base imbalance is an abnormality of the human body's normal balance of acids and bases that causes the plasma pH to deviate out of the normal range (7.35 to 7.45). In the fetus, the normal range differs based on which umbilical vessel is sampled (umbilical vein pH is normally 7.25 to 7.45; umbilical artery pH is normally 7.18 to 7.38). [1]

  7. Buffer solution - Wikipedia

    en.wikipedia.org/wiki/Buffer_solution

    Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications. In nature, there are many living systems that use buffering for pH regulation. For example, the bicarbonate buffering system is used to regulate the pH of blood, and bicarbonate also acts as a buffer in the ocean.

  8. Carbaminohemoglobin - Wikipedia

    en.wikipedia.org/wiki/Carbaminohemoglobin

    Most importantly, the binding of carbon dioxide to hemoglobin helps buffer blood pH by preventing carbonic acid from decreasing the pH. [6] Although, the carbaminohemoglobin protein interacts with another protein (like hemoglobin) found in red blood cells, this interaction only takes place in the bloodstream and its products can be expelled.

  9. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    Carbon dioxide, a by-product of cellular respiration, is dissolved in the blood. From the blood it is taken up by red blood cells and converted to carbonic acid by the carbonate buffer system. Most carbonic acid then dissociates to bicarbonate and hydrogen ions. One of the buffer systems present in the body is the blood plasma buffering system.