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  2. Drug abuse retinopathy - Wikipedia

    en.wikipedia.org/wiki/Drug_abuse_retinopathy

    The duration of cocaine use is a major contributing factor to the severity of the adverse retinal effect. [24] Cocaine use is also associated with retinal hemorrhage due to the general increase in blood pressure and blood vessel occlusion within the retina. [25]

  3. Pupillary response - Wikipedia

    en.wikipedia.org/wiki/Pupillary_response

    Dilation and constriction of the pupil Pupillary response is a physiological response that varies the size of the pupil between 1.5 mm and 8 mm, [ 1 ] via the optic and oculomotor cranial nerve. A constriction response ( miosis ), [ 2 ] is the narrowing of the pupil, which may be caused by scleral buckles or drugs such as opiates / opioids or ...

  4. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    In Western Australia under the Misuse of Drugs Act 1981 4.0g of cocaine is the amount of prohibited drugs determining a court of trial, 2.0g is the amount of cocaine required for the presumption of intention to sell or supply and 28.0g is the amount of cocaine required for purposes of drug trafficking.

  5. Addiction-related structural neuroplasticity - Wikipedia

    en.wikipedia.org/wiki/Addiction-related...

    The effect of these structural changes on behavior is uncertain and studies have produced conflicting results. Two studies [ 18 ] [ 19 ] have shown that an increase in dendritic spine density due to cocaine exposure facilitates behavioral sensitization , while two other studies [ 20 ] [ 21 ] produce contradicting evidence.

  6. Optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Optic_neuropathy

    Optic neuropathy is damage to the optic nerve from any cause. The optic nerve is a bundle of millions of fibers in the retina that sends visual signals to the brain. Damage and death of these nerve cells, or neurons, leads to characteri

  7. Cocaethylene - Wikipedia

    en.wikipedia.org/wiki/Cocaethylene

    Cocaethylene has a higher affinity for the dopamine transporter than does cocaine, but has a lower affinity for the serotonin and norepinephrine transporters. [ 11 ] [ 12 ] A 2000 study by Hart et al. on the effects of intravenous cocaethylene in humans found that "cocaethylene has pharmacological properties in common with cocaine, but is less ...

  8. Cocaine intoxication - Wikipedia

    en.wikipedia.org/wiki/Cocaine_intoxication

    Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...

  9. Cocaine dependence - Wikipedia

    en.wikipedia.org/wiki/Cocaine_dependence

    In the United States, past year cocaine users in 2019 was 5.5 million for people aged 12 or older. When broken into age groups, ages 12–17 had 97,000 users; ages 18–25 had 1.8 million users and ages 26 or older had 3.6 million users. [10] Past year cocaine users with a cocaine use disorder in 2019 was 1 million for people aged 12 or older.