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CSL Plasma is a subsidiary of its sister company CSL Behring, itself a subsidiary of CSL Limited, a biotechnology company based in Melbourne, Australia. [2] [ P 2] It is headquartered in Boca Raton, Florida, [1] and operates a total of 320 collection centers in the United States, [P 3] and a further 19 more in other nations including China, Hungary, and Germany as of 2023.
CSL was founded in 1916 as Commonwealth Serum Laboratories, an Australian government body focused on vaccine manufacture. [4] Under the first director, William Penfold, [5] CSL commenced operation in the vacant Walter and Eliza Hall Institute building at the Royal Melbourne Hospital in 1918 before moving to its purpose-built Parkville premises in the following year.
The blood volume is 70 ml/kg body weight in adult males, 65 ml/kg in adult females and 70-75 ml/kg in children (1 year old and over). [ 5 ] [ 6 ] Total Blood Volume has been measured manually by the use of carbon monoxide (CO) as a tracer for more than 100 years and was first proposed by French scientists Grehant and Quinquaud in 1882.
CSL Behring is a biopharmaceutical company, manufacturing plasma-derived and recombinant therapeutic products. [2] The company is a combination of Behringwerke, founded in 1904 in Marburg, Germany by Emil von Behring, and the Commonwealth Serum Laboratories (CSL), established in Australia in 1916 to provide vaccines to the people of Australia, as well as other companies acquired since 2004.
% = Using the deviation from desirable weight, the BV ratio (ml/kg), i.e. Ideal Blood Volume, can be determined. The machine was tested in clinical studies for the treatment of a broad range of medical conditions related to Intravascular Volume Status, such as anemia, [ 4 ] congestive heart failure, [ 5 ] sepsis, [ 6 ] CFS, [ 7 ] Hyponatremia ...
It ultimately depends on the state and city the plasma center is located in, but diligent and qualified plasma donors can make anywhere from an extra $360 per month to about $1,000 per month. What ...
In this article, all values (except the ones listed below) denote blood plasma concentration, which is approximately 60–100% larger than the actual blood concentration if the amount inside red blood cells (RBCs) is negligible.
In the simple mono-compartmental case the volume of distribution is defined as: = /, where the in practice is an extrapolated concentration at time = 0 from the first early plasma concentrations after an IV-bolus administration (generally taken around 5 min - 30 min after giving the drug).