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Antiuricosuric drugs raise serum uric acid levels and lower urine uric acid levels. These drugs include all diuretics, pyrazinoate, pyrazinamide, ethambutol, niacin, and aspirin. [5] The NSAID diclofenac has an antiuricosuric action, which may be partly responsible for the extraordinary toxicity of this drug in vultures. [6]
Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...
Corticosteroids, prescription medications that can quickly reduce inflammation in the body. ... or joint damage, your provider may prescribe medication to lower uric acid levels. These can help ...
This reduces the risk of urate precipitates, since allantoin is five to ten times more soluble than uric acid. In contrast to rasburicase, pegloticase is PEGylated to increase its elimination half-life from about eight hours to ten to twelve days, and to decrease the immunogenicity of the foreign uricase protein. This modification allows for a ...
A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism.In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. [1]
Lifestyle changes, including reducing dietary salt, increasing exercise and losing weight can help to reduce blood pressure. [9] Thiazides and thiazide-like diuretics have been in constant use since their introduction in 1958. Decades as a cornerstone of hypertension treatment show how well these drugs perform for most patients. [10]
Throughout Drop Acid, Dr. Perlmutter offers suggestions and tips on maintaining lower uric values as well as a road map to addressing these hidden dangers. Per the description it also features ...
Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia . Probenecid was developed as an alternative to caronamide [ 1 ] to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and ...
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