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  2. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    Significant toxicity from benzodiazepines can occur in the elderly as a result of long-term use. [112] Benzodiazepines , along with antihypertensives and drugs affecting the cholinergic system, are the most common cause of drug-induced dementia affecting over 10 percent of patients attending memory clinics.

  3. Neurogenic bowel dysfunction - Wikipedia

    en.wikipedia.org/wiki/Neurogenic_bowel_dysfunction

    Damage to the defecation centre within the medulla oblongata of the brain can lead to bowel dysfunction. A stroke or acquired brain injury may lead to damage to this centre in the brain. Damage to the defecation centre can lead to a loss of coordination between rectal and anal contractions and also a loss of awareness of the need to defecate. [12]

  4. Amlodipine - Wikipedia

    en.wikipedia.org/wiki/Amlodipine

    [2] [10] When used by people with liver problems, and in elderly individuals, doses should be reduced. [10] Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type. [10] Amlodipine was patented in 1982, and approved for medical ...

  5. Levamlodipine - Wikipedia

    en.wikipedia.org/wiki/Levamlodipine

    Levamlodipine , also known as levoamlodipine or S-amlodipine is a pharmacologically active enantiomer of amlodipine. [1] Amlodipine belongs to the dihydropyridine group of calcium channel blocker used as an antihypertensive and antianginal agent. [2] It was approved by the U.S. FDA in December 2019 and is currently marketed under the brand name ...

  6. Fecal incontinence - Wikipedia

    en.wikipedia.org/wiki/Fecal_incontinence

    Surgery involving the rectum (e.g. lower anterior resection, often performed for colorectal cancer), radiotherapy directed at the rectum, and inflammatory bowel disease can cause scarring, which may result in the walls of the rectum becoming stiff and inelastic, reducing compliance. Reduced rectal storage capacity may lead to urge incontinence ...

  7. Volvulus - Wikipedia

    en.wikipedia.org/wiki/Volvulus

    Volvulus causes severe pain and progressive injury to the intestinal wall, with accumulation of gas and fluid in the portion of the bowel obstructed. [11] Ultimately, this can result in necrosis of the affected intestinal wall, acidosis, and death. This is known as a closed-loop obstruction because there exists an isolated ("closed") loop of bowel.

  8. Calcium channel blocker toxicity - Wikipedia

    en.wikipedia.org/wiki/Calcium_channel_blocker...

    Thus they are commonly present in many people's homes. In young children one pill may cause serious health problems and potentially death. [8] The calcium channel blocker that caused the greatest number of deaths in 2010 in the United States was verapamil. [2] This agent is believed to cause more heart problems than many of the others. [2]

  9. Steatorrhea - Wikipedia

    en.wikipedia.org/wiki/Steatorrhea

    The absence of bile secretion can cause the feces to turn gray or pale. Bile is responsible for the brownish color of feces. Bile is responsible for the brownish color of feces. In addition to this, bile also plays a role in fat absorption, where dietary lipids are combined so that pancreatic lipases can hydrolyze them before going towards the ...

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