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In mycology a tissue or feature is said to be amyloid if it has a positive amyloid reaction when subjected to a crude chemical test using iodine as an ingredient of either Melzer's reagent or Lugol's solution, producing a blue to blue-black staining. The term "amyloid" is derived from the Latin amyloideus ("starch-like"). [1]
To date, 37 human proteins have been found to form amyloid in pathology and be associated with well-defined diseases. [2] The International Society of Amyloidosis classifies amyloid fibrils and their associated diseases based upon associated proteins (for example ATTR is the group of diseases and associated fibrils formed by TTR). [3]
Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. [1] The disease is caused when a person's antibody-producing cells do not function properly and produce abnormal protein fibers made of components of antibodies called light chains.
Amyloid light chains deposition in shoulder joint causes enlarged shoulders, also known as "shoulder pad sign". [18] Amyloid light chain depositions can also cause bilateral symmetric polyarthritis. [18] The deposition of amyloid proteins in the bone marrow without causing plasma cell dyscrasias is called amyloidoma. It is commonly found in ...
There is evidence that eating amyloid fibers may lead to amyloidosis. This evidence is based on studies in cattle, chickens, mice, and cheetahs. [ 22 ] Thus, in a sense, SAA amyloidosis may be considered a contagious disease, although whether this occurs or is important in the development of naturally occurring amyloidosis remains unknown.
Acute-phase serum amyloid A proteins (A-SAAs) are secreted during the acute phase of inflammation.These proteins have several roles, including the transport of cholesterol to the liver for secretion into the bile, the recruitment of immune cells to inflammatory sites, and the induction of enzymes that degrade extracellular matrix.
International Journal of Medicinal Mushrooms: Journal of Fungi: MDPI (Basel, Switzerland) 2015– Journal of Mycology: Manhattan 1885–1908, replaced by Mycologia: Medical Mycology: Taylor and Francis, Volume 1–23 published as Sabouraudia and Volumes 24–33 published as Journal of Medical and Veterinary Mycology: 1972– MycoKeys: Pensoft ...
The Journal was established in 1994 as AMYLOID: The International Journal of Experimental & Clinical Investigation until the change of name in 2004. [2] The impact factor in 2017 was 4.048. [3] Dr. Alan Cohen was the founding editor and from 1994 until 2010 the first Editor-in-Chief of Amyloid: The Journal of Protein Folding Disorders. [4]